Iwona Lewy-Trenda, Agnieszka Wierzchniewska-Lawska

Hyalinizing Trabecular Adenoma of the Thyroid Gland - a Report of Two Cases

Chair and Department of Pathomorphology, University Medical School, Lodz

Abstract

Hyalinizing trabecular adenoma (HTA) is a specific variant of thyroid adenoma with a particular histological pattern. Immunohistochemistry is the best way of differentiating these adenomas. Of special interest is a strong positive cytoplasmic reaction for MIB-1. In FNAB and intra-operative examination HTA is usually misdiagnosed as a papillary carcinoma. Histological examination of paraffin-embedded material and immunohistochemical stainings provide a correct diagnosis.

Address for correspondence and reprint requests to:
I. Lewy-Trenda, M. D.,
Department of Pathomorphology,
Czechoslowacka 8/10, 92-216 Lodz.