Kazimierz Pietrzak(1), Wojciech Olszewski(2)

DNA Ploidy as a Prognostic Factor in Patients with Ovarian Carcinoma

1)Department of Gynaecological Oncology,
2)Department of Pathology of the M. Skˆodowska-Curie Memorial Cancer Center and Institute of Oncology, Warszawa

Abstract

The aim of this work was to establish the dependence between survival and time to progression and the factor which is considered as risk factor i. e type of DNA ploidy. The DNA ploidy was evaluated in 33 cases of ovary carcinoma selected from 314 cases. The statistically significant difference between the 5 years survivals in patients with DNA aneuploidy and patients with DNA diploidy was observed (13.6% vs 60.9%). What was also found out, was the statistically significant difference between the 5 years survivals without the progression of disease in patients with DNA aneuploidy and patients with DNA diploidy (13.6% vs 55.9%).

Address for correspondence and reprint requests to:
K. Pietrzak M. D.,
Department of Gynaecological Oncology,
M. Sklodowska-Curie Memorial Cancer Center,
Roentgena 5, 02-784 Warszawa.